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D2.1.5—DNA replication prerequisite

DNA replication in S phase creates sister chromatids that remain attached until their separation during mitosis or meiosis later in division.

Syllabus
First assessment 2025
Objective
D2.1.5
Level
SL

Exam analysis

Chance of appearing2%of analysed past papers
Latest appearanceMay 2024
Most common paperPaper1
Typical marks1

Common command terms

  • Distinguish

Scoring notes

Common mistake
Counting chromosomes and chromatids as the same thing after DNA replication.

Recent exam appearances

May 2024Paper2 ["SL"] · TZ12(a)(ii)[ 1 ]D2.1.5—DNA replication prerequisite
May 2017Paper1 ["SL"] · TZ15[ 1 ]D2.1.5—DNA replication prerequisite
May 2017Paper1 ["SL"] · TZ214[ 1 ]D2.1.5—DNA replication prerequisite
Practice this objective

Coverage 2017–2024 · Updated 16 Jul 2026

Concept essentials

  • DNA replication occurs in S phase of interphase.
  • After replication, each chromosome consists of two sister chromatids.
  • Sister chromatids remain joined at the centromere before separation.
  • DNA amount doubles from G1 to G2 before division.
ConceptIB Biology SL