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D3.2 Inheritance

Inheritance explains how alleles, chromosomes, meiosis, pedigrees, linkage, variation and statistical tests predict genetic outcomes across generations in inheritance problems.

Syllabus
First assessment 2025
Topic
D3.2
Level
SL

Exam analysis

Chance of appearing48%of analysed past papers
Latest appearanceNovember 2025
Most common paperPaper1
Typical marks1–2

Most tested objectives

Common question formats

  • Definition or recall
  • Structured response
  • Diagram interpretation
  • Data analysis
  • Calculation
  • Graph interpretation
  • Comparison

Recent exam appearances

November 2025Paper1B ["SL"] · TZ34(d)[ 3 ]D3.2.9—ABO blood groups
November 2025Paper1A ["SL"] · TZ120[ 1 ]D3.2.13—Pedigree charts
May 2025Paper2 ["SL"] · TZ15(c)[ 3 ]D3.2.5—Dominant and recessive alleles
May 2025Paper2 ["SL"] · TZ34(b)(ii)[ 2 ]D3.2.13—Pedigree charts
May 2025Paper2 ["SL"] · TZ34(b)(i)[ 1 ]D3.2.13—Pedigree charts
Practice this topic

Coverage 2010–2025 · Updated 16 Jul 2026

Objective notes

15 learning objectives
D3.2.1Haploid gametes + fusion = diploid zygote

• Haploid gametes fuse during fertilization to form a diploid zygote

• Diploid organisms usually carry two alleles for each autosomal gene

D3.2.2Genetic crosses in flowering plants

• Genetic crosses track parental, F1, and F2 generations using Punnett grids

• Flowering plant crosses control pollen transfer to study inheritance ratios

D3.2.3Genotype

• Genotype is the allele combination inherited for a gene or genes

• Homozygous genotypes have matching alleles; heterozygous genotypes have different alleles

D3.2.4Phenotype

• Phenotype is the observable characteristic or trait

• Phenotype can be determined by genotype, environment, and their interaction

D3.2.5Dominant and recessive alleles

• Dominant alleles are expressed in heterozygotes

• Recessive alleles are expressed when no dominant allele masks them

D3.2.6Phenotypic plasticity

• Phenotypic plasticity is environment-driven phenotype change without genotype change

• It depends on altered gene expression and can be adaptive

D3.2.7Phenylketonuria (PKU)

• PKU is an autosomal recessive disorder affecting phenylalanine metabolism

• Low-phenylalanine diet and newborn screening reduce harmful effects

D3.2.8SNPs and multiple alleles

• SNPs are single-base differences that can create different alleles

• Populations can have multiple alleles, but diploid individuals carry at most two

D3.2.9ABO blood groups

• ABO blood group is controlled by IA, IB, and i alleles

• IA and IB are codominant; i is recessive, producing four blood phenotypes

D3.2.10Incomplete dominance and codominance

• Codominance expresses both heterozygous alleles, as in AB blood type

• Incomplete dominance gives an intermediate heterozygote phenotype

D3.2.11Sex determination

• Human chromosomal sex is usually determined by XX or XY chromosome combination

• The SRY/TDF region on the Y chromosome directs testis development

D3.2.12Haemophilia

• Haemophilia is an X-linked recessive blood-clotting disorder

• Carrier females and affected males are represented with X-linked allele notation

D3.2.13Pedigree charts

• Pedigree charts show family inheritance across generations

• Patterns help infer autosomal dominant, autosomal recessive, or sex-linked inheritance

D3.2.14Continuous variation

• Continuous variation often results from polygenic inheritance plus environment

• Human skin colour, height, and body mass show many intermediate phenotypes

D3.2.15Box-and-whisker plots

• Box-and-whisker plots summarize non-normal continuous data

• They show median, quartiles, interquartile range, maximum/minimum, and outliers

ConceptIB Biology SL