Course review

D2.1 Cell and nuclear division

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Learning objective

D2.1.1—Generation of new cells

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• All cells arise from pre-existing parent cells by cell division • Division produces daughter cells for growth, replacement, repair, or reproduction

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Learning objective

D2.1.2—Cytokinesis

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• Cytokinesis splits cytoplasm after nuclear division • Animal cells use a contractile ring; plant cells form a vesicle-derived cell plate

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Learning objective

D2.1.3—Equal and unequal cytokinesis

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• Equal cytokinesis gives daughter cells similar amounts of cytoplasm • Unequal cytokinesis occurs in oogenesis and yeast budding

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Learning objective

D2.1.4—Roles of mitosis and meiosis

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• Mitosis maintains chromosome number for growth, repair, and asexual reproduction • Meiosis halves chromosome number for gametes and generates genetic diversity

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Learning objective

D2.1.5—DNA replication prerequisite

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• DNA replication in interphase produces chromosomes with sister chromatids • Sister chromatids remain joined at centromeres until separation

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Learning objective

D2.1.6—Shared features

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• Mitosis and meiosis both condense chromatin into movable chromosomes • Histones, nucleosomes, spindle microtubules, and motor proteins organize movement

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Learning objective

D2.1.7—Phases of mitosis

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• Prophase condenses chromosomes; metaphase aligns them at the equator • Anaphase separates chromatids; telophase reforms nuclei, producing identical nuclei

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Learning objective

D2.1.8—Identification of mitosis phases

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• Mitosis phases are identified in diagrams, micrographs, and root-tip squashes • Chromosome condensation, equator alignment, separation, and nuclear membranes are cues

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Learning objective

D2.1.9—Meiosis as reduction division

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• Meiosis has two nuclear divisions after one round of DNA replication • Homologous chromosomes separate in meiosis I, producing haploid nuclei

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Learning objective

D2.1.10—Down syndrome

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• Non-disjunction is failed separation of homologues or sister chromatids in meiosis • Down syndrome usually results from trisomy 21 after non-disjunction

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Learning objective

D2.1.11—Meiosis generates variation

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• Crossing over at chiasmata exchanges DNA between non-sister chromatids • Random orientation of bivalents and fertilization create new allele combinations

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