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IB Biology HL 1.1.2 Semi-conservative replication and experimental inference Question Bank

Practise IB Biology HL 1.1.2 by analysing isotope evidence and distinguishing competing DNA-replication models.

Syllabus
First assessment 2025
Course
Biology HL
Level
HL

Exam points

  • Infer the replication model from density bands after successive generations.
  • Predict mixed, light or heavy DNA fractions under alternative replication assumptions.
  • Evaluate experimental controls and the evidence linking base pairing to semi-conservative copying.

D1.1.2—Semi-conservative replication question 1

[Maximum number: 3]

The confirmation of DNA as the genetic material, together with the elucidation of its structure by Crick and Watson, had a profound effect on modern biology.

Outline the reason that DNA replication is described as semi-conservative.

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