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A2.3.1 (HL)—Common structural features

Viruses share a protein capsid enclosing nucleic acid, lack cellular machinery, and can reproduce only by exploiting the metabolism of a living host cell.

Syllabus
First assessment 2025
Objective
A2.3.1
Level
HL

Exam analysis

Chance of appearing5%of analysed past papers
Latest appearanceNovember 2025
Most common paperPaper2
Typical marks1

Common command terms

  • State
  • Label
  • Describe
  • Justify

Scoring notes

Common mistake
Describing viruses as cells that merely lack a nucleus instead of recognizing that they are acellular.

Recent exam appearances

November 2025Paper1A ["HL"] · TZ313[ 1 ]A2.3.1 (HL)—Common structural features
November 2025Paper1A ["HL"] · TZ112[ 1 ]A2.3.1 (HL)—Common structural features
May 2025Paper2 ["HL"] · TZ25(c)[ 2 ]A2.3.1 (HL)—Common structural features
May 2025Paper2 ["HL"] · TZ14(b)[ 1 ]A2.3.1 (HL)—Common structural features
May 2025Paper2 ["HL"] · TZ14(a)[ 1 ]A2.3.1 (HL)—Common structural features
Practice this objective

Coverage 2021–2025 · Updated 15 Jul 2026

Viruses Share a Basic Genetic Package

HL only

Viruses contain genetic material enclosed in a protein coat, and many also have a lipid envelope with attachment proteins.

The genome stores instructions for making viral components; the capsid protects it and helps deliver it into a host cell. Envelopes are host-derived membranes carrying viral proteins that recognize receptors.

Describe a virus structurally:

  • DNA or RNA genome
  • capsid proteins
  • optional envelope and spikes
  • no independent ribosomes

An enveloped virus may bind a host receptor with a spike protein, fuse membranes, and release its genome into the cytoplasm.

A virus particle has structure but lacks the complete machinery for independent metabolism and protein synthesis.

Common structural features

HL only

Assessment in practice

1 marks
How it is assessed

This objective is assessed through structured response, commonly using State / Label / Describe.

Command terms

State / Label / Describe / Justify

What earns marks

Build the answer around this relationship: Every virus has genetic material enclosed by a protein capsid.

Watch for

Describing viruses as cells that merely lack a nucleus instead of recognizing that they are acellular.

Representative question

Question 1

[Maximum number: 1]

Describe one reason that viruses are not considered to be living.

Build A Virus Answer

HL only

A strong HL virus answer usually combines two moves: define the boundary, then explain the mechanism or consequence. Viruses have DNA or RNA plus a capsid but lack the machinery for independent metabolism. Their diversity is described by genome, capsid, and envelope. Lambda phage lets you contrast lytic takeover with lysogenic integration. Origin questions require competing hypotheses and polyphyly. Evolution questions require mutation, recombination, short cycles, large populations, and examples such as influenza or HIV.

  • Definition: non-cellular obligate parasite with genome plus capsid, lacking cytoplasm/ribosomes/metabolic enzymes.
  • Structure: compare genome, capsid shape, and envelope status.
  • Replication: lytic = takeover and lysis; lysogenic = prophage integration and induction.
  • Origins: likely polyphyletic, with virus-first, escaped-gene, and regressive hypotheses.
  • Evolution: rapid variation explains vaccine updates and treatment resistance.

Concept essentials

  • Every virus has genetic material enclosed by a protein capsid.
  • Viruses lack cytoplasm, ribosomes, and independent metabolic machinery.
  • Viral replication occurs only inside a suitable living host cell.
  • A virus is an obligate intracellular parasite rather than a cellular organism.
ConceptIB Biology HL