A2.3.5 (HL)—Several origins of viruses

Viruses are probably polyphyletic, with different lineages arising through escaped genetic elements, reduction of cellular parasites, or ancient pre-cellular replicators.

Syllabus
First assessment 2025
Objective
A2.3.5
Level
HL

Viruses May Have Multiple Evolutionary Origins

HL only

The diversity of viruses is consistent with more than one evolutionary origin, rather than one simple family tree from a single first virus.

Some viruses resemble escaped genetic elements, some may descend from reduced cellular organisms, and others may have assembled from ancient replicators. Similar functions can evolve independently, so shared genes must be interpreted with context.

When comparing origins, ask:

  • what genes and structures are shared
  • whether cellular ancestors are plausible
  • whether similarity could be convergent
  • how host association changed

A capsid gene shared by distant viruses may indicate transfer or convergent function; it does not alone prove one direct ancestor.

‘All viruses evolved from one virus’ is stronger than the evidence supports.

Build A Virus Answer

HL only

A strong HL virus answer usually combines two moves: define the boundary, then explain the mechanism or consequence. Viruses have DNA or RNA plus a capsid but lack the machinery for independent metabolism. Their diversity is described by genome, capsid, and envelope. Lambda phage lets you contrast lytic takeover with lysogenic integration. Origin questions require competing hypotheses and polyphyly. Evolution questions require mutation, recombination, short cycles, large populations, and examples such as influenza or HIV.

  • Definition: non-cellular obligate parasite with genome plus capsid, lacking cytoplasm/ribosomes/metabolic enzymes.
  • Structure: compare genome, capsid shape, and envelope status.
  • Replication: lytic = takeover and lysis; lysogenic = prophage integration and induction.
  • Origins: likely polyphyletic, with virus-first, escaped-gene, and regressive hypotheses.
  • Evolution: rapid variation explains vaccine updates and treatment resistance.

Concept essentials

  • Viral diversity is consistent with multiple evolutionary origins rather than one universal ancestor.
  • The progressive hypothesis derives viruses from escaped cellular genetic elements.
  • The regressive hypothesis derives viruses from cellular parasites that lost independence.
  • The virus-first hypothesis derives some viruses from ancient self-replicating systems.
  • Similar host dependence may have evolved convergently in separate viral lineages.