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CAIE A-Level Biology 12.2.4 The Link Reaction

Practise converting three-carbon pyruvate to acetyl-CoA by decarboxylation and dehydrogenation in the matrix, accounting for CO₂ and reduced NAD.

Syllabus
2028–2030
Course
Biology 9700
Level
A2

Exam points

  • remove carbon dioxide from three-carbon pyruvate during decarboxylation
  • oxidise the remaining fragment while reducing NAD during dehydrogenation
  • attach the two-carbon acetyl group to coenzyme A for delivery to the Krebs cycle

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