Edexcel IGCSE Biology 2.6B Stem cells in medicine
Practise applying stem-cell ideas to medical treatments, including bone marrow transplants, heart repair, rejection risk and treatment trials.
- Syllabus
- First assessment 2019
- Course
- Biology 4BI1
Practise applying stem-cell ideas to medical treatments, including bone marrow transplants, heart repair, rejection risk and treatment trials.
The human heart pumps blood when its muscle tissue contracts.
Diagram 1 shows a human heart and a cross-section through its ventricles.

Diagram 1
Scientists are investigating the use of stem cells to repair damaged hearts.
The stem cells are injected into the ventricle muscle tissue.
Explain why stem cells could repair a damaged heart.
An explanation that makes reference to three of the following points:
- (stem cells can) differentiate / can become muscle cells / can make any cell types / stem cells are undifferentiated / unspecialised cells / eq
- stem cells divide / (carry out) mitosis / cell division
stems cells
are
pluripotent / totipotent /
multipotent
3ci 2
The stem cells are obtained from the person who has the damaged heart.
Explain why using stem cells from the same person is better than using stem cells from a different person.
An explanation that makes reference to two of the following points:
- cells have same DNA / genes / alleles / eq
- same antigens / tissue type / blood group
- less risk of rejection / not rejected
- no immune response / by immune system / no need to take immunosuppressants
- no risk of infection / disease spread
No
immune
rejection
= two
marks
3cii 2