IB Biology SL B1.2.5 Protein Denaturation Question Bank

Practise IB Biology SL B1.2.5 by explaining how temperature or pH changes alter a protein’s three-dimensional structure and biological activity.

Exam points

Explain how pH or temperature changes protein shape, active sites and biological activity.
Interpret denaturation evidence to distinguish altered conformation from changed amino-acid sequence.

[Maximum number: 3]

The diagrams represent the structure of a protein before and after it has become denatured.

Native protein

(a)

Outline one cause of denaturation in proteins.

[ 1 ]

(b)

Explain how denaturation affects the activity of an enzyme.

[ 2 ]

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