IB Biology SL B1.2.5 Effect of Ph and Temperature Questions

Practise IB Biology SL B1.2.5 by explaining how unsuitable temperature or pH disrupts protein shape and function.

Exam points

Identify increased temperature, extreme pH, salts or heavy metals as conditions that can denature proteins.
Explain how denaturation disrupts weak bonds and changes protein conformation, including an enzyme active site.
Relate loss of three-dimensional structure to reduced substrate binding and reduced or lost biological activity.

[Maximum number: 1]

The diagrams represent the structure of a protein before and after it has become denatured.

Native protein

Outline one cause of denaturation in proteins.

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a	increase in temperature/heat;
b	change of pH;
c	salt;
d	heavy metals;