• Integration lets interacting parts coordinate an overall biological function
• Systems interact across molecular, cellular, organ, organism, and ecosystem levels
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2
Learning objective
C3.1.2—Hierarchy in multicellular organisms
New
• Cells form tissues, organs, organ systems, and whole organisms
• Emergent properties arise when subsystems interact, such as gut peristalsis and absorption
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Start with the concept explanation, then practise to create mastery evidence.
3
Learning objective
C3.1.3—Integration of organs
New
• Organs are integrated by nervous signals, hormones, and blood transport
• Transport links nutrients, gases, wastes, hormones, and energy substrates between organs
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Start with the concept explanation, then practise to create mastery evidence.
4
Learning objective
C3.1.4—Brain as information integration organ
New
• The brain integrates sensory input and coordinates complex responses
• Cerebral hemispheres, cerebellum, hypothalamus, and medulla have distinct roles
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5
Learning objective
C3.1.5—Spinal cord
New
• The spinal cord links brain and peripheral nervous system
• It integrates unconscious processes such as reflex arcs
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6
Learning objective
C3.1.6—Input through sensory neurons
New
• Sensory neurons carry impulses from receptors to spinal cord and brain
• Inputs may reach cerebral hemispheres for conscious perception
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Start with the concept explanation, then practise to create mastery evidence.
7
Learning objective
C3.1.7—Output through motor neurons
New
• Motor neurons carry impulses from CNS to skeletal muscle effectors
• Voluntary muscle contraction is coordinated through cerebral hemispheres
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8
Learning objective
C3.1.8—Nerves as bundles
New
• Nerves are bundles of sensory and motor nerve fibres in connective tissue
• Mixed nerves carry impulses both to and from the CNS
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9
Learning objective
C3.1.9—Pain reflex arcs
New
• Pain reflexes are rapid involuntary withdrawal responses
• Reflex arcs use receptors, sensory neurons, relay neurons, motor neurons, and skeletal muscle
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Start with the concept explanation, then practise to create mastery evidence.
10
Learning objective
C3.1.10—Cerebellum role
New
• The cerebellum coordinates timing and force of skeletal muscle contractions
• It maintains balance, posture, and smooth learned movements
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11
Learning objective
C3.1.11—Melatonin and sleep
New
• The pineal gland secretes melatonin according to light-dark cycles
• Melatonin modulates sleep timing as part of circadian rhythms
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12
Learning objective
C3.1.12—Epinephrine (adrenaline)
New
• Adrenal glands secrete epinephrine during stress or danger
• It increases heart rate, ventilation, and respiratory substrate availability
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13
Learning objective
C3.1.13—Hypothalamus and pituitary control
New
• The hypothalamus links nervous inputs to endocrine control
• Pituitary hormones regulate glands including thyroid, gonads, adrenals, and mammary glands
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14
Learning objective
C3.1.14—Heart rate feedback control
New
• Baroreceptors monitor blood pressure; chemoreceptors monitor CO₂, pH, and O₂
• The medulla adjusts sinoatrial node activity by sympathetic and parasympathetic nerves
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15
Learning objective
C3.1.15—Ventilation rate feedback control
New
• Chemoreceptors detect CO₂-driven pH changes in blood and cerebrospinal fluid
• The medulla alters diaphragm and intercostal muscle activity to change ventilation rate
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Start with the concept explanation, then practise to create mastery evidence.
16
Learning objective
C3.1.16—Peristalsis control
New
• The CNS controls voluntary swallowing and egestion
• The enteric nervous system coordinates involuntary peristalsis in gut smooth muscle
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Mistakes
Start with the concept explanation, then practise to create mastery evidence.