• ATP is a small soluble nucleotide and universal energy currency
• It links energy-yielding respiration to energy-requiring cellular processes
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Mistakes
Start with the concept explanation, then practise to create mastery evidence.
2
Learning objective
C1.2.2—Life processes using ATP
New
• ATP supplies active transport, anabolic synthesis, and movement
• Examples include membrane pumps, macromolecule synthesis, and chromosome movement
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Start with the concept explanation, then practise to create mastery evidence.
3
Learning objective
C1.2.3—ATP ↔ ADP interconversions
New
• ATP hydrolysis to ADP and phosphate releases energy for coupled reactions
• Respiration phosphorylates ADP to ATP; ATP is recycled rather than stored
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Start with the concept explanation, then practise to create mastery evidence.
4
Learning objective
C1.2.4—Cell respiration system
New
• Cell respiration is enzyme-controlled release of energy from organic compounds
• Carbon compounds are oxidized stepwise so energy can be transferred to ATP
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Start with the concept explanation, then practise to create mastery evidence.
5
Learning objective
C1.2.5—Anaerobic vs. aerobic respiration in humans
New
• Aerobic respiration uses oxygen and mitochondria, producing CO₂, water, and high ATP
• Anaerobic respiration in human cytoplasm produces lactate and low ATP
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Start with the concept explanation, then practise to create mastery evidence.
6
Learning objective
C1.2.6—Variables affecting rate
New
• Rate depends on metabolic demand, organism size, oxygen, substrate, temperature, and pH
• Respirometers measure oxygen uptake while soda lime absorbs CO₂
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Mistakes
Start with the concept explanation, then practise to create mastery evidence.
7
Learning objective
C1.2.7 (HL)—NAD as hydrogen carrier
New
• NAD accepts hydrogen during oxidation/dehydrogenation reactions
• Reduced NAD carries electrons and protons to the electron transport chain
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Start with the concept explanation, then practise to create mastery evidence.
8
Learning objective
C1.2.8 (HL)—Glycolysis
New
• Glycolysis converts glucose to two pyruvate molecules in the cytoplasm
• It is a linear pathway with substrate-level ATP and reduced NAD net yield
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Start with the concept explanation, then practise to create mastery evidence.
9
Learning objective
C1.2.9 (HL)—Pyruvate → lactate
New
• Pyruvate accepts hydrogen from reduced NAD to form lactate
• Regenerated NAD allows glycolysis to continue
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Mastery
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Start with the concept explanation, then practise to create mastery evidence.
10
Learning objective
C1.2.10 (HL)—Anaerobic respiration in yeast
New
• Yeast converts pyruvate to ethanol and CO₂ during alcoholic fermentation
• Fermentation regenerates NAD for glycolysis and is used in baking and brewing
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Start with the concept explanation, then practise to create mastery evidence.
11
Learning objective
C1.2.11 (HL)—Link reaction
New
• Pyruvate is oxidized and decarboxylated in the mitochondrial matrix
• Acetyl groups join coenzyme A to form acetyl-CoA for the Krebs cycle
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12
Learning objective
C1.2.12 (HL)—Krebs cycle
New
• Acetyl-CoA combines with oxaloacetate to form citrate
• The cycle regenerates oxaloacetate and yields CO₂, ATP, reduced NAD, and reduced FAD
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Start with the concept explanation, then practise to create mastery evidence.
13
Learning objective
C1.2.13 (HL)—Electron transport chain
New
• Reduced NAD and FAD donate electrons to carriers in the inner mitochondrial membrane
• Electron transfers release energy while coenzymes are reoxidized
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14
Learning objective
C1.2.14 (HL)—Proton gradient generation
New
• Electron transport energy pumps protons from matrix to intermembrane space
• The inner membrane maintains a proton gradient and membrane potential
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Mastery
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15
Learning objective
C1.2.15 (HL)—Chemiosmosis
New
• Protons flow through ATP synthase back into the matrix
• ATP synthase couples proton flow to ADP phosphorylation by chemiosmosis
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Mastery
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16
Learning objective
C1.2.16 (HL)—Oxygen as terminal electron acceptor
New
• Oxygen is the terminal electron acceptor at the end of the chain
• Oxygen combines with electrons and protons to form metabolic water
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17
Learning objective
C1.2.17 (HL)—Lipids vs. carbohydrates as substrates
New
• Lipids yield more ATP and metabolic water per gram because they are more reduced
• Carbohydrates are easier to hydrolyse and enter glycolysis quickly
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Mastery
0
Attempts
0
Mistakes
Start with the concept explanation, then practise to create mastery evidence.