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B2.2.9 (HL)—Vesicles in cells

Vesicles transport proteins and other cargo between organelles, the plasma membrane, and extracellular space during secretion, uptake, and intracellular delivery.

Syllabus
First assessment 2025
Objective
B2.2.9
Level
HL

Exam analysis

Chance of appearing2%of analysed past papers
Latest appearanceMay 2025
Most common paperPaper1
Typical marks1

Common command terms

  • Identify

Scoring notes

Common mistake
Putting the Golgi apparatus before rough ER in the protein export route.

Recent exam appearances

May 2025Paper1A ["HL"] · TZ215[ 1 ]B2.2.9 (HL)—Vesicles in cells
May 2017Paper1 ["HL"] · TZ23[ 1 ]B2.2.9 (HL)—Vesicles in cells
Practice this objective

Coverage 2017–2025 · Updated 15 Jul 2026

Concept essentials

  • Protein export commonly follows rough ER to Golgi apparatus to plasma membrane.
  • Secretory vesicles can move enzymes out of cells by exocytosis.
  • Clathrin helps membranes indent during coated vesicle formation.
  • Vesicles link organelles, membranes, and extracellular release pathways.
ConceptIB Biology HL