B2.2.8 (HL)—Golgi apparatus
The Golgi apparatus modifies, sorts, and packages proteins from the rough ER into vesicles for membranes, lysosomes, or secretion routes.
- Syllabus
- First assessment 2025
- Objective
- B2.2.8
- Level
- HL
The Golgi apparatus modifies, sorts, and packages proteins from the rough ER into vesicles for membranes, lysosomes, or secretion routes.

Coverage 2013–2013 · Updated 15 Jul 2026
The Golgi apparatus receives vesicles, modifies their contents and sorts them into new vesicles for different destinations.
Different cisternae contain enzymes that alter proteins or lipids as cargo moves through the stack. Sorting signals direct cargo to the plasma membrane, lysosome or another compartment.
Follow cargo: arrival vesicle; cisternal modification; sorting signal; destination vesicle.
A protein processed in the ER can be glycosylated further in the Golgi and packaged for secretion.
The Golgi is not simply storage: its value is sequential processing plus destination-specific sorting.
This objective is assessed through multiple choice, commonly using Explain / Identify.
Explain / Identify
Build the answer around this relationship: The Golgi apparatus receives vesicles from the rough ER.
Treating the Golgi apparatus as the site of polypeptide synthesis.
Representative question
The diagram summarizes the production and secretion of digestive enzymes in an exocrine gland cell of the pancreas.
Which cell organelle is involved at Y ?
Rough endoplasmic reticulum
Golgi apparatus
Lysosome
Ribosome
B
HL structure-function answers should link organelle compartments to the process they support. Mitochondria use cristae, intermembrane space, and matrix; chloroplasts use thylakoid membranes, thylakoid space, and stroma. Protein export is a route: rough ER makes entry-pathway proteins, Golgi modifies and sorts, vesicles bud and fuse with targets.