B2.1.5—Osmosis and aquaporins

Osmosis moves water passively across selectively permeable membranes, often through aquaporins, toward regions with higher solute concentration; Aquaporins make this water movement faster and more physiologically responsive.

Syllabus
First assessment 2025
Objective
B2.1.5
Level
HL

Exam analysis

Chance of appearing2%of analysed past papers
Latest appearanceMay 2025
Most common paperPaper1B
Typical marks1–2

Common command terms

  • Describe
  • Identify
  • Define
  • State
  • Explain
  • Distinguish

Scoring notes

Common mistake
Describing movement of solute instead of net movement of water.

Recent exam appearances

May 2025Paper1B ["HL"] · TZ32(b)(i)[ 2 ]B2.1.5—Osmosis and aquaporins
May 2025Paper1B ["HL"] · TZ32(a)[ 1 ]B2.1.5—Osmosis and aquaporins
May 2024Paper3 ["HL"] · TZ22(a)[ 1 ]B2.1.5—Osmosis and aquaporins
Practice this objective

Coverage 2024–2025 · Updated 15 Jul 2026

Osmosis Is Water Movement Through a Selective Membrane

Osmosis is passive net movement of water across a membrane that is permeable to water but not freely permeable to the solutes involved.

Water molecules move randomly both ways. A difference in solute concentration creates a difference in water potential, so net water movement is from the lower-solute, higher-water-potential side toward the higher-solute, lower-water-potential side.

Aquaporins are selective protein pores that greatly increase water permeability. They change the rate of osmosis, not the direction set by the water-potential difference.

A cell in a solution with higher solute concentration than its cytoplasm loses water and shrinks; aquaporins allow that volume change to occur faster.

Do not state only that 'water follows solute'. Identify the selectively permeable membrane, compare the two solutions and distinguish net movement from random movement in both directions.

Osmosis and aquaporins

Assessment in practice

1–2 marks
How it is assessed

This objective is assessed through structured response, commonly using Describe / Identify / Define.

Command terms

Describe / Identify / Define / State / Explain / Distinguish

What earns marks

Build the answer around this relationship: Osmosis is passive net movement of water across a selectively permeable membrane.

Watch for

Describing movement of solute instead of net movement of water.

Representative question

Question 1

[Maximum number: 4]

Describe transport across cell membranes by osmosis.

SL Transfer: Choose The Transport Route

The SL membrane model is a decision system. The bilayer forms because phospholipids are amphipathic, and the hydrophobic core creates selective permeability. Small non-polar molecules diffuse directly; water moves by osmosis and often through aquaporins; ions and polar molecules use channels or transporters; pumps use ATP for movement against gradients. Proteins and glycocalyx components add transport, recognition, and model evidence.

  • Bilayers self-assemble from amphipathic phospholipids.
  • The hydrophobic core blocks ions and large or hydrophilic molecules.
  • Simple diffusion, osmosis, facilitated diffusion, and active transport are chosen by molecule type and gradient.
  • Integral/peripheral proteins and the glycocalyx add transport and recognition roles.
  • The fluid mosaic model explains mobile mixed membrane components.

Concept essentials

  • Osmosis is passive net movement of water across a selectively permeable membrane.
  • Water moves toward higher solute concentration or lower water potential.
  • Aquaporins are protein channels that increase water movement across membranes.
  • Cell volume can change quickly when aquaporins increase water uptake.