IB Biology HL A3.2.5 Molecular clocks Question Bank
Practise IB Biology HL A3.2.5 by relating sequence substitutions to divergence time and interpreting molecular evidence in cladograms.
- Syllabus
- First assessment 2025
- Course
- Biology HL
- Level
- HL
Practise IB Biology HL A3.2.5 by relating sequence substitutions to divergence time and interpreting molecular evidence in cladograms.
The evolutionary clock estimates the time elapsed since species separated from a common ancestor based on fossil evidence. The graph shows the number of differences in the DNA sequences (nucleotide substitutions) coding for certain polypeptides in 11 closely related mammals.

State the relationship between divergence time and number of substitutions.
direct relationship
OR positive correlation
OR
the greater the divergence time, the greater the substitutions;
Marking guidance:
Do not accept "linear relationship" on
its own.
1
max