B3.2.11 (HL)—Tissue fluid in capillaries
Tissue fluid forms when capillary hydrostatic pressure forces plasma out, while plasma proteins help draw fluid back near venule ends.
- Syllabus
- First assessment 2025
- Objective
- B3.2.11
- Level
- HL
Tissue fluid forms when capillary hydrostatic pressure forces plasma out, while plasma proteins help draw fluid back near venule ends.
Tissue fluid is formed when hydrostatic pressure at the arteriole end of a capillary forces some plasma out through the capillary wall.
Small solutes and water leave, but cells and most plasma proteins remain in the blood. As pressure falls and osmotic effects change along the capillary, some fluid is reabsorbed.
Compare hydrostatic and osmotic forces along the capillary; state why filtration changes with position.
Higher blood pressure at the arterial end favors filtration, while lower pressure toward the venous end favors return of fluid.
Tissue fluid is not whole blood: red cells and large proteins normally stay inside the capillary.
HL transport adds pressure and route systems. Tissue fluid forms by capillary pressure and returns by osmotic pull or lymph. Double circulation separates pulmonary and systemic routes. The heart creates directional pressure with chambers, septum, valves, and cycle timing. Plants add root pressure and phloem pressure-flow translocation.