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B2.3.3—Stem cell niches in adult humans

Adult stem cell niches are local tissue environments that maintain stem cells, regulate their division, and control activation or differentiation.

Syllabus
First assessment 2025
Objective
B2.3.3
Level
HL

Concept essentials

  • A stem cell niche is a local environment that regulates stem cell behaviour.
  • Niches can maintain stem cells in an undifferentiated state.
  • Niche signals can activate division and guide differentiation.
  • Bone marrow and hair follicle bulge regions are examples of adult stem cell niches.
ConceptIB Biology HL