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A1.2.7—Differences between DNA and RNA

DNA and RNA differ in sugar, bases, strand structure, and usual length, giving each nucleic acid distinct roles in cells.

Syllabus
First assessment 2025
Objective
A1.2.7
Level
HL

Exam analysis

Chance of appearing4%of analysed past papers
Latest appearanceMay 2025
Most common paperPaper1
Typical marks1–3

Common command terms

  • Identify
  • State
  • Distinguish
  • Determine

Scoring notes

Common mistake
Listing a DNA feature as an RNA feature, especially thymine, uracil, ribose, or deoxyribose.

Recent exam appearances

May 2025Paper2 HL · TZ33(a)[ 1 ]A1.2.7—Differences between DNA and RNA
May 2019Paper2 HL · TZ27(a)[ 3 ]A1.2.7—Differences between DNA and RNA
May 2019Paper1 HL · TZ17[ 1 ]A1.2.7—Differences between DNA and RNA
May 2016Paper1 HL · TZ05[ 1 ]A1.2.7—Differences between DNA and RNA
Practice this objective

Coverage 2016–2025 · Updated 14 Jul 2026

Concept essentials

  • Differences between DNA and RNA should be described using precise molecular vocabulary.
  • Structure and information must be kept separate: backbones provide continuity while bases carry sequence meaning.
  • Exam answers should match the command term and avoid adding unsupported extra claims.
ConceptIB Biology HL