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D1.3 Mutation and gene editing

Mutation and gene editing explain how DNA sequence changes arise, affect proteins, create variation and can be studied or altered deliberately.

Syllabus
First assessment 2025
Topic
D1.3
Level
—

What you’ll learn

10 learning objectives

Choose one objective for a focused lesson, or study the complete topic.

Exam analysis

An aggregate view of how the complete D1.3 Mutation and gene editing appears across past papers.

Chance of appearing13%of analysed past papers
Latest appearanceNovember 2025
Most common paperPaper2

Most tested objectives

  1. D1.3.2—Base substitution consequences11 questions
  2. D1.3.4—Causes of mutation10 questions
  3. D1.3.1—Gene mutations9 questions

Common question formats

  • Definition or recall
  • Process explanation
  • Comparison
  • Evaluation
  • Diagram interpretation
  • Calculation

Exam question appearances

November 2025Paper1A ["SL"] · TZ17[ 1 ]D1.3.6—Consequences in germ vs. somatic cells
November 2025Paper2 ["HL"] · TZ15(c)[ 2 ]D1.3.4—Causes of mutation
November 2025Paper1B ["SL"] · TZ14(d)(ii)[ 1 ]D1.3.4—Causes of mutation
November 2025Paper1B ["SL"] · TZ14(d)(i)[ 1 ]D1.3.4—Causes of mutation
November 2025Paper1B ["SL"] · TZ14(b)[ 1 ]D1.3.4—Causes of mutation
Practice this topic

1 original exam-style questions based on the patterns above.

Coverage 2010–2025 · Updated 16 Jul 2026

Study checklistD1.3 Mutation and gene editing