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D1.1 DNA replication

DNA replication copies genetic information through template strands, complementary pairing, enzyme action, proofreading, and laboratory amplification or separation techniques used to analyse DNA.

Syllabus
First assessment 2025
Topic
D1.1
Level

What you’ll learn

9 learning objectives

Choose one objective for a focused lesson, or study the complete topic.

Exam analysis

An aggregate view of how the complete D1.1 DNA replication appears across past papers.

Chance of appearing29%of analysed past papers
Latest appearanceNovember 2025
Most common paperPaper1

Most tested objectives

  1. D1.1.4—PCR and gel electrophoresis36 questions
  2. D1.1.8 (HL)—Functions in replication15 questions
  3. D1.1.2—Semi-conservative replication13 questions

Common question formats

  • Definition or recall
  • Diagram interpretation
  • Structured response
  • Process explanation
  • Calculation
  • Data analysis
  • Comparison

Exam question appearances

November 2025Paper2 ["HL"] · TZ19(a)[ 4 ]D1.1.9 (HL)—DNA proofreading
November 2025Paper1A ["HL"] · TZ19[ 1 ]D1.1.4—PCR and gel electrophoresis
November 2025Paper1A ["SL"] · TZ37[ 1 ]D1.1.3—Role of helicase and DNA polymerase
November 2025Paper2 ["SL"] · TZ32(b)[ 1 ]D1.1.4—PCR and gel electrophoresis
November 2025Paper1A ["HL"] · TZ310[ 1 ]D1.1.4—PCR and gel electrophoresis
Practice this topic

4 original exam-style questions based on the patterns above.

Coverage 2010–2025 · Updated 16 Jul 2026

Study checklistD1.1 DNA replication