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Edexcel IAL Biology 7.11 Sliding filament muscle contraction

Begin with calcium binding to troponin, move tropomyosin, cycle myosin attachment and power strokes with ATP and link filament overlap to sarcomere shortening.

Syllabus
First assessment 2019
Course
Biology YBI11
Level
A2

Exam points

  • Explain how calcium, troponin and tropomyosin expose actin binding sites.
  • Describe ATP binding and hydrolysis during myosin release and power strokes.
  • Interpret sarcomere or force evidence through cross-bridge formation and overlap.

7.11—Sliding filament theory question 1

[Maximum number: 3]

Movement in mammals results from interactions between muscles, tendons, ligaments and bones.

The graph shows the relationship between the force of muscle contraction and the velocity of muscle contraction.

Figure for Question 7.11—Sliding filament theory question 1 — Edexcel A-Level Biology A2

The greater the number of cross bridges formed between actin and myosin the greater the force of contraction of a muscle.

Explain the relationship between the force and the velocity of contraction of a muscle.
(3)

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