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CAIE A-Level Biology 6.2.8 Effects of Mutations on Polypeptides

Practise predicting silent, missense, nonsense or frameshift outcomes by translating affected codons and linking altered primary structure or early stops to protein function.

Syllabus
2028–2030
Course
Biology 9700
Level
AS

Exam points

  • translate original and mutated codons before comparing polypeptide primary structure
  • explain broader downstream change after a frameshift than after one substitution
  • connect altered R-group interactions or early stop codons with changed protein function

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