CAIE A-Level Biology Practical Assessment Skills
Practise the AO3 skills assessed in Paper 3 and Paper 5, including experimental work, observation, presentation, analysis, planning and evaluation.
- Syllabus
- 2028–2030
- Course
- Biology 9700
- Level
- AS
Practise the AO3 skills assessed in Paper 3 and Paper 5, including experimental work, observation, presentation, analysis, planning and evaluation.
Alveolar macrophages are cells of the immune system that remain in the alveolar region of the gas exchange system. The macrophages protect against infection caused by pathogens that have been inhaled.
Alveolar macrophages have the same cell structures as typical animal cells.
Fig. 2.1 is a diagram of an alveolar macrophage showing:
- some of the cell structures that would be visible using an electron microscope
- a newly formed phagocytic vacuole (phagosome) containing two cells of Mycobacterium tuberculosis.

Fig. 2.1
The cell structures with the functions described in Table 2.1 are not shown in Fig. 2.1.
Complete Fig. 2.1 by drawing and labelling the cell structures described in Table 2.1.
structures should be labelled and drawn with enough detail not to be mistaken for another structure
all three correct = 2 marks
one or two correct = 1 mark
all three structures correctly drawn but no labels = 1 mark
- roughly spherical organelle within the nucleus labelled as nucleolus
- minimum of one single membrane-bound tubular sac labelled as, smooth endoplasmic reticulum / smooth ER / SER R if dots (ribosomes) drawn and resembles RER
- two, short lines or cylinders, not parallel to each other labelled as (pair of) centrioles
R if inside the nucleus
The graph shows the percentage of tuberculosis (TB) patients who were also known to be infected with HIV, from 2004 to 2011.

Which statement about the graph is correct?
From 2004 to 2010, the percentage of TB patients with HIV infection in region P increased from 3% to 69%.
From 2005 to 2011, the percentage of TB patients with HIV infection increased more rapidly in region P than in regions outside region P.
From 2006 to 2011, the percentage of TB patients with HIV infection in regions outside region P doubled.
From 2007 to 2011, the percentage of TB patients with HIV infection globally increased from 20% to 30%.
B