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CAIE A-Level Biology 6.2.7 Substitution, Insertion and Deletion Mutations

Practise classifying substitutions, insertions and deletions from paired sequences, regrouping downstream triplets and deciding whether an in-frame change or frameshift occurs.

Syllabus
2028–2030
Course
Biology 9700
Level
AS

Exam points

  • identify substitution when one base pair is replaced without changing sequence length
  • identify insertion or deletion and regroup all downstream triplets from the mutation site
  • distinguish a frameshift from an in-frame change involving a multiple of three bases

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