CAIE A-Level Biology AS 6.2 Protein Synthesis Questions

Practise CAIE AS Biology 6.2 by converting DNA and RNA sequences into polypeptides, tracing RNA processing, and judging how mutations alter protein products.

Exam points

Define a gene as a DNA nucleotide sequence coding for a polypeptide.
Use the universal code to map DNA triplets and mRNA codons to amino acids, start and stop signals.
Infer mRNA from the transcribed DNA strand and identify the non-transcribed strand.
Trace transcription and translation through RNA polymerase, mRNA codons, tRNA anticodons and ribosomes.
Explain intron removal and exon joining as a primary transcript becomes mature eukaryotic mRNA.
Compare substitution, insertion and deletion effects on codons and resulting polypeptide sequence or function.

Covered syllabus points

6.2.1—Gene 6.2.2—Universal genetic code and codons 6.2.3—Transcription and translation roles 6.2.4—DNA strands in transcription 6.2.5—Post-transcriptional modification 6.2.6—Gene mutations 6.2.7—Types of mutations 6.2.8—Effects on polypeptide produced

[Maximum number: 1]

One gene provides the code for the production of which type of molecule?

amino acid

DNA

nucleotide

polypeptide

[Maximum number: 1]

The mRNA codons ACU, ACC, ACA and ACG all code for the same amino acid, threonine.
Which anticodons could specify an amino acid other than threonine?
1 UCA
2 ACC
3 UGU
4 UGC

1,3 and 4

1 and 2

2 and 3

3 and 4 only

[Maximum number: 1]

Which statements correctly describe the process of translation?
1 The nucleotide sequence on an mRNA molecule is used to produce a specific amino acid chain.

2 A section of DNA is copied into an mRNA molecule by RNA polymerase.
3 A polypeptide is produced because anticodons on tRNA molecules attach to mRNA codons through peptide bonds.

1 and 2

1 and 3

1 only

2 and 3

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Covered syllabus points

Question 1

Question 2

Question 3