CAIE A-Level Biology AS 3.1.3 Enzyme Action Hypotheses Questions

Evaluate enzyme-action hypotheses by linking active-site models to substrate binding and experimental reaction evidence.

Syllabus
2028–2030
Course
Biology 9700
Level
AS

Exam points

  • Evaluate hypotheses about enzyme action using active-site models, substrate binding and reaction evidence.

CAIE A-Level Biology AS 3.1.3 Enzyme Action Hypotheses Questions question 1

[Maximum number: 1]

Influenza virus has an enzyme called neuraminidase which breaks down glycoproteins in the surface membrane of the cell that the virus will infect. The glycoprotein binds to the active site of neuraminidase by induced fit.

Which statements about the induced fit hypothesis of enzyme action are correct?
1 The active site must have the same shape as the substrate for them to bind together.

2 This enzyme is less likely to be affected by non-competitive inhibitors than an enzyme working by the lock-and-key mechanism.

3 The substrate is converted to product by specific R-groups in the active site just like the lock-and-key mechanism.

A

1 and 2

B

2 and 3

C

2 only

D

3 only

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