A Unity and Diversity

A1.1 Water

A1.2 Nucleic acids

A2.1 Origins of cells

A2.2 Cell structure

A2.3 Viruses [HL only]

A3.1 Diversity of organisms

A3.2 Classification and cladistics [HL only]

A4.1 Evolution and speciation

A4.2 Conservation of biodiversity

B Form and Function

B1.1 Carbohydrates and lipids

B1.2 Proteins

B2.1 Membranes and membrane transport

B2.2 Organelles and compartmentalization

B2.3 Cell specialization

B3.1 Gas exchange

B3.2 Transport

B3.3 Muscle and motility [HL only]

B4.1 Adaptation to environment

B4.2 Ecological niches

C Interaction and Interdependence

C1.1 Enzymes and metabolism

C1.2 Cell respiration

C1.3 Photosynthesis

C2.1 Chemical signalling [HL only]

C2.2 Neural signalling

C3.1 Integration of body systems

C3.2 Defence against disease

C4.1 Populations and communities

C4.2 Transfers of energy and matter

D Continuity and Change

D1.1 DNA replication

D1.2 Protein synthesis

D1.2.1—Transcription

D1.2.2—Hydrogen bonding in transcription

D1.2.3—DNA template stability

D1.2.4—Transcription for gene expression

D1.2.5—Translation

D1.2.6—Roles in translation

D1.2.7—Complementary base pairing

D1.2.8—Genetic code features

D1.2.9—Using genetic code table

D1.2.10—Elongation of polypeptide

D1.2.11—Mutations changing protein structure

D1.2.12 (HL)—Directionality

D1.2.13 (HL)—Initiation of transcription at promoter

D1.2.14 (HL)—Non-coding sequences in DNA

D1.2.15 (HL)—Post-transcriptional modification

D1.2.16 (HL)—Alternative splicing

D1.2.17 (HL)—Translation initiation

D1.2.18 (HL)—Polypeptide modification

D1.2.19 (HL)—Amino acid recycling by proteasomes

D1.3 Mutation and gene editing

D2.1 Cell and nuclear division

D2.2 Gene expression [HL only]

D2.3 Water potential

D3.1 Reproduction

D3.2 Inheritance

D3.3 Homeostasis

D4.1 Natural selection

D4.2 Stability and change

D4.3 Climate change

IB Biology HL D1.2.18 (HL)—Polypeptide modification Question Bank

• Newly made polypeptides may be folded, cleaved, or chemically modified

• Preproinsulin processing to active insulin is a key example

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