Edexcel IGCSE Biology 5.19B Cloned mammals
Practise cloning mammals from adult cells, including nuclear transfer stages, embryo data calculations and evaluation of cloning evidence.
- Syllabus
- First assessment 2019
- Course
- Biology 4BI1
Practise cloning mammals from adult cells, including nuclear transfer stages, embryo data calculations and evaluation of cloning evidence.
Read the passage below.
Use the information in the passage and your own knowledge to answer the questions that follow.
Toystory
Toystory is a bull who was born in 2001. The photograph shows Toystory.

In the world of dairy farming Toystory is a famous bull. He fathered 500000 offspring but did not mate with any cows. He was able to father so many offspring because his semen was collected and then used to fertilise cows using artificial insemination.
Toystory's mother was a high milk producer and his father was a popular bull. He was sold for $ 4000 by his owner to a specialist breeding company called Genex.
Genex started to collect semen from Toystory when he was four years old. The semen is carefully collected, using a teaser animal and an artificial rubber vagina.
The semen is divided into many separate samples. These samples are put in small straws and frozen in liquid nitrogen. The straws can then be sold and sent to dairy farmers around the world to inseminate their cows. A total of 2.4 million samples of semen from Toystory was sold in more than 50 countries around the world.
Toystory's reputation grew as the offspring he fathered went on to be high milk producers. His semen straws sold for over $ 60 each. Bull semen can now be sold as sexed or unsexed samples, with sexed samples being more expensive to purchase.
Toystory was highly valued because his offspring produced large quantities of milk of a desired composition. His semen was effective at getting cows pregnant, his daughters gave birth easily and were strong. He had a rare mix of fertility, genetics and appearance.
25 One of his daughters sold for $ 300000 in 2009. His record number of offspring is unlikely to be beaten. This is because bulls are often retired earlier as new genetic advances are discovered.
Scientists are now using cloning to produce animals.
Describe the stages that are required to clone a bull.
A description that makes reference to four of the following points:
- nucleus from (body) cell of bull
- insert this nucleus into enucleated egg cell
- electric shock
- mitosis / cell division
- embryo into uterus / womb
- surrogate mother
reject from udder
reject egg cell from bull
exp
Give two advantages of using cloning rather than selective breeding to produce offspring.
1
2
An explanation that makes reference to two of the following points
- genetically identical / no genetic variation / same (combination of) alleles
- quicker process
exp