Edexcel IGCSE Biology 3.36B mutation effects on phenotype
Practise using codon tables and mutation evidence to explain why DNA changes may not alter proteins, enzymes or phenotype.
- Syllabus
- First assessment 2019
- Course
- Biology 4BI1
Practise using codon tables and mutation evidence to explain why DNA changes may not alter proteins, enzymes or phenotype.
The sequence of bases on one strand of a section of DNA is
TAC CGT AAT TAT
The table shows different mRNA codons for some amino acids.

Explain why most genetic mutations have no effect on the phenotype of an organism.
Use the information in the table and your own knowledge in your answer.
An explanation that makes reference to three of the following points:
Accept (amino acid W has two codes / (amino acid) Y has two codes / eq
Accept same polypeptide
1. some sequences / codons / different
codes / different bases / may code for same amino acid /eq
2. (same amino acid so) no change in protein / no change in enzyme / protein has same function / eq
3. may not affect bonding / (3D) shape / active site of enzyme / still binds to substrate / eq
4. mutation / allele / gene, may be recessive / not expressed / eq
5. non-coding DNA / eq