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Edexcel A-Level Biology AS 2.16 Cystic Fibrosis Gene Mutation Effects Questions

Trace CFTR gene changes to faulty protein function, chloride and water movement, and viscous mucus, then connect mucus blockage to gas exchange, digestion, infection and fertility.

Syllabus
First assessment 2019
Course
Biology YBI11
Level
AS

Exam points

  • Explain how CFTR mutations produce faulty protein, altered chloride or water movement and thick mucus.
  • Link airway mucus to blocked diffusion surfaces, infection risk and reduced gas exchange.
  • Apply CF mucus effects to pancreatic digestion, reproductive function and variable mutation outcomes.

Edexcel A-Level Biology AS 2.16 Cystic Fibrosis Gene Mutation Effects Questions question 1

[Maximum number: 6]

Cystic fibrosis is an inherited disorder.

The diagrams show a cross section through a trachea from a person without cystic fibrosis and from a person with cystic fibrosis.

Figure for Question Edexcel A-Level Biology AS 2.16 Cystic Fibrosis Gene Mutation Effects Questions question 1 — Edexcel A-Level Biology AS

Explain why cystic fibrosis causes the differences shown in the diagrams.

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