CAIE A-Level Biology AS 8.2.4 Oxygen Dissociation Curve Questions

Interpret the oxygen dissociation curve and factors affecting haemoglobin affinity using evidence from each question and mark scheme.

Syllabus
2028–2030
Course
Biology 9700
Level
AS

Exam points

  • Interpret the oxygen dissociation curve and explain factors affecting haemoglobin affinity.

CAIE A-Level Biology AS 8.2.4 Oxygen Dissociation Curve Questions question 1

[Maximum number: 3]

During one cardiac cycle:
- blood enters the heart from the lungs and from the rest of the body
- blood leaves the heart to be transported to the lungs and to the rest of the body.

Fig. 3.2 shows the oxygen dissociation curve for adult haemoglobin in a person who does not have sickle cell anaemia.

Fig. 3.2

Fig. 3.2

Compared to Fig. 3.2, the oxygen dissociation curve for adult haemoglobin in a person with sickle cell anaemia is shifted to the right.

The uptake of oxygen by haemoglobin in the lungs and the release of oxygen by haemoglobin in respiring tissues is different in a person with sickle cell anaemia compared with a person who does not have the disease.

With reference to Fig. 3.2, state and explain these differences.
uptake of oxygen
release of oxygen

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