ConceptConceptDocsDocuments

CAIE A-Level Biology 11.2.2 Hybridoma Production of Monoclonal Antibodies

Practise sequencing antigen injection, spleen B-cell isolation, tumour-cell fusion, hybridoma screening and cloning before culturing identical antibody-producing cells.

Syllabus
2028–2030
Course
Biology 9700
Level
AS

Exam points

  • immunise an animal and isolate spleen B-lymphocytes making the target antibody
  • fuse B cells with tumour cells to combine antibody secretion and unlimited division
  • screen, clone and culture the selected hybridoma before harvesting monoclonal antibody

No Question Bank Yet

Questions will appear here when available.