CAIE A-Level Biology AS 11.1 The Immune System Questions

Practise phagocyte recognition and digestion, self versus non-self antigen responses, the primary lymphocyte sequence and memory-cell protection on re-exposure.

Syllabus
2028–2030
Course
Biology 9700
Level
AS

Exam points

  • Describe phagocytosis from receptor binding to phagosome, lysosome fusion and digestion.
  • Distinguish self from non-self antigens, using graft rejection and self-reactive T-cell evidence.
  • Sequence primary response: macrophage presentation, T-helper activation, B-cell cloning into plasma cells.
  • Explain how memory cells produce a faster, larger secondary response, using antibody-concentration graphs.

Question 1

[Maximum number: 1]

Some responses made by cells of the immune system to a pathogen are listed.
1 mitosis
2 recognises a pathogen
3 produces memory cells
4 secretes enzymes
Which responses are correct for phagocytes?

A

1, 2, 3 and 4

B

1, 2 and 3 only

C

1 and 3 only

D

2 and 4 only

Question 2

[Maximum number: 1]

A person's blood group is determined by antigens present on the red blood cells.
The table shows the antigens and antibodies in the blood of people with different blood groups.

Table for Question 2 — CAIE A-Level Biology AS

During a blood transfusion, it is essential that the person receiving the blood does not have antibodies to the donor's blood.

Which blood groups can be given to a person with blood group A B ?

A

A B only

B

O only

C

A and B only

D

A, B, AB and O

Question 3

[Maximum number: 1]

The events listed occur during the primary immune response to a specific pathogen.
1 activation of B-lymphocyte to produce plasma cells and memory cells
2 phagocytosis of invading pathogens by macrophages
3 T-helper cell activation and production of T-killer cells
4 expression of antigens on phagocyte cell surface
5 production and release of antibodies
Which row identifies a correct sequence of events?

A

5

1

2

4

2

4

3

1

last

4

2

1

5

3

4

2

3

1

5

All question bank results loaded