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1.2.6—Prokaryotes vs eukaryotes

Syllabus
9700–2028–2029
Objective
1.2.6
Level
AS

The prokaryote–eukaryote contrast is about organisation, not just size

Prokaryotes and eukaryotes both have a cell-surface membrane, cytoplasm, DNA and ribosomes. The key structural contrast is that eukaryotes organise DNA and many cell processes inside membrane-bound organelles, whereas prokaryotes do not.

Structural feature Prokaryotes Eukaryotes
Cell organisation Usually unicellular; no membrane-bound organelles May be unicellular or multicellular; membrane-bound organelles present
Genetic material Circular DNA in the cytoplasm, not enclosed by a nucleus Linear chromosomes inside a nucleus
Ribosomes 70S 80S in the cytoplasm; 70S in mitochondria and chloroplasts
Typical size Usually about 1–5 µm in diameter Often larger; plant cells may be about 10–100 µm across
Cell wall, when present Peptidoglycan Cellulose in plants or chitin in fungi

The eukaryotic nucleus and other compartments keep different reactions in controlled local conditions. A prokaryote’s simpler organisation leaves its circular DNA in the cytoplasm and has no double-membrane organelles. These are structural patterns to compare together, not a single size test.

Both cell types contain DNA, ribosomes and a membrane. A large bacterium can still be prokaryotic, and a unicellular yeast cell can still be eukaryotic; identify the cell type from DNA location, ribosome type and organelle organisation rather than apparent size alone.

ConceptA-Level CAIE Biology AS