The HL extension asks how complex cell organization could arise and become useful. Endosymbiosis explains the origin of mitochondria and chloroplasts using bacterial evidence. Differentiation explains how cells with the same genome become specialized through different gene expression and proteomes. Multicellularity explains why adhesion, communication, and differentiation allowed larger bodies and division of labour.
- Endosymbiosis: organelle origin supported by bacterial-style evidence.
- Differentiation: same genome, different gene expression, different proteome.
- Multicellularity: adhesion, communication, differentiation.
- Advantages: larger body size and cell specialization.