A cell is the smallest unit that can maintain a boundary, exchange matter and energy, and reproduce its information.
Life processes require coordinated chemistry. A membrane keeps useful gradients, internal reactions transform resources, and genetic information guides maintenance and reproduction; isolated molecules cannot perform the full integrated set.
Look for the minimum package:
- boundary and internal chemistry
- energy and matter exchange
- information and reproduction
A bacterium can take in nutrients, use a proton gradient to make ATP, copy its DNA and divide; a purified enzyme cannot do all of these tasks alone.
A virus may contain genetic material and reproduce only inside a host, so “contains DNA” alone does not make it a fully independent cell.