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D1.1 DNA replication

DNA replication copies genetic information through template strands, complementary pairing, enzyme action, proofreading, and laboratory amplification or separation techniques used to analyse DNA.

Syllabus
First assessment 2025
Topic
D1.1
Level
HL

What you’ll learn

9 learning objectives

Choose one objective for a focused lesson, or study the complete topic.

Exam analysis

An aggregate view of how the complete D1.1 DNA replication appears across past papers.

Chance of appearing30%of analysed past papers
Latest appearanceNovember 2025
Most common paperPaper1

Most tested objectives

  1. D1.1.4—PCR and gel electrophoresis16 questions
  2. D1.1.8 (HL)—Functions in replication14 questions
  3. D1.1.5—Applications6 questions

Common question formats

  • Definition or recall
  • Diagram interpretation
  • Structured response
  • Process explanation
  • Calculation
  • Data analysis
  • Comparison

Exam question appearances

November 2025Paper2 ["HL"] · TZ19(a)[ 4 ]D1.1.9 (HL)—DNA proofreading
November 2025Paper1A ["HL"] · TZ19[ 1 ]D1.1.4—PCR and gel electrophoresis
November 2025Paper1A ["HL"] · TZ310[ 1 ]D1.1.4—PCR and gel electrophoresis
May 2025Paper1A ["HL"] · TZ19[ 1 ]D1.1.9 (HL)—DNA proofreading
November 2024Paper1 ["HL"] · TZ026[ 1 ]D1.1.7 (HL)—Leading vs. lagging strand
Practice this topic

4 original exam-style questions based on the patterns above.

Coverage 2013–2025 · Updated 16 Jul 2026

Study checklistD1.1 DNA replication