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AP Biology 6.7.A: Types of Mutations and Protein Effects

Practise AP Biology 6.7.A questions by identifying point, frameshift, nonsense and silent mutations, then predicting how DNA changes alter RNA, protein synthesis and phenotype.

Syllabus
Effective Fall 2025
Course
AP Biology

Exam points

  • classify point, frameshift, nonsense and silent mutations from a DNA sequence or reading-frame change
  • predict how a mutation changes codons, amino-acid sequence, protein length or protein function
  • connect mutation effects to altered protein production and beneficial, detrimental or neutral phenotypes

6.7.A—Describe the various types of mutation question 1

[Maximum number: 1]

A particular genetic disorder results from a single change in the amino acid sequence coded for in a gene. Parts of the sequence in normal and mutated genes are shown below. Normal: TAC CTC GTG GAC TGA GGT CTC Mutated: TAC CTC GTG GAC TGA GGT CAC

Second Base

Second Base

Based on the codon chart above, which of the following amino acid changes is most likely found in the mutated protein?

Figure 1. A pedigree of three generations of a family that have a high frequency of a particular genetic condition

Figure 1. A pedigree of three generations of a family that have a high frequency of a particular genetic condition

A

Glu → Val

B

Val → Glu

C

Glu → Pro

D

Pro → Val

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