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AP Biology 4.6 B Describe the Effects of Disruptions to the Cell Cycle on the Cell or Organism Questions

Practise AP Biology 4.6.B questions by predicting how checkpoint failure, altered growth signals and chromosome errors affect cells and organisms.

Syllabus
Effective Fall 2025
Course
AP Biology

Exam points

  • predict how checkpoint or tumor-suppressor disruptions affect cell division
  • explain how contact inhibition or growth-pathway changes can promote cancer
  • distinguish uncontrolled proliferation from apoptosis or chromosome-segregation defects

AP Biology 4.6 B Describe the Effects of Disruptions to the Cell Cycle on the Cell or Organism Questions question 1

[Maximum number: 1]

The p53 protein is a transcription factor that regulates a cell's progression through the cell cycle after DNA is damaged by ultraviolet (UV) radiation. The p53 pathway is shown in Figure 1.

Figure 1. The role of p53 in regulating cell cycle progression in response to DNA damage

Figure 1. The role of p53 in regulating cell cycle progression in response to DNA damage

Based on Figure 1, explain how a mutation to p53 may lead to an increased risk of cancer.

Figure for Question AP Biology 4.6 B Describe the Effects of Disruptions to the Cell Cycle on the Cell or Organism Questions question 1 — AP Biology

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