7.2 Natural Selection

Syllabus
2025
Topic
7.2
Level

Learning objectives

Why Phenotypic Variation Matters for Selection

Natural selection acts on phenotypic variation: observable or functional differences among individuals in a population. Without relevant variation, a selective pressure cannot favor one phenotype over another.

Population contains phenotypic variants → the environment applies a selective pressure → variants differ in survival or reproduction → fitness differs → the population's trait frequencies can change across generations.

Environments change, so a phenotype that increases fitness under one set of biotic or abiotic conditions may have no advantage—or may decrease fitness—under another. Variation therefore gives a population multiple possible responses to changing pressures.

Natural selection acts directly on phenotypes, not on a hidden genotype in isolation. It does not make every difference adaptive; only variations that affect survival or reproductive success in the current environment influence fitness.

From Molecular Variation to Organism Fitness

Variation in the type or number of molecules inside cells can change how cells function. Those functional differences can alter an organism's ability to survive and reproduce in a particular environment.

Molecular type or amount differs → cellular process changes → organism performance or phenotype changes → survival or reproduction changes under specific conditions → fitness differs.

Consider enzyme variants that function differently at different temperatures. If one variant maintains a needed cellular reaction more effectively under the current temperature, organisms carrying it may perform and reproduce better. If temperature changes, the relative advantage can also change.

A population containing different molecular variants is more likely to include individuals whose cellular machinery functions well under a range of environments, increasing the population's capacity to survive and reproduce when conditions differ.

More of a molecule is not automatically better, and one molecular type is not universally superior. Fitness depends on the molecule's effect on function in the particular environment.