• Neurons carry electrical impulses in the nervous system
• Motor, sensory, and relay neurons differ in axon, dendrite, and cell body arrangement
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2
Learning objective
C2.2.2—Resting potential generation
New
• Sodium-potassium pumps use ATP to move 3 Na⁺ out and 2 K⁺ in
• Ion gradients make the resting axon polarized at about -70 mV
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3
Learning objective
C2.2.3—Nerve impulses as action potentials
New
• A nerve impulse is a propagated action potential along a nerve fibre
• Stimulus-triggered sodium influx reverses membrane polarity
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4
Learning objective
C2.2.4—Variation in impulse speed
New
• Larger axon diameter lowers resistance and increases impulse speed
• Myelin sheaths and nodes of Ranvier enable faster saltatory conduction
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5
Learning objective
C2.2.5—Synapses as junctions
New
• Synapses connect neurons to neurons, muscles, or glands
• Chemical synapses transmit one way across a narrow synaptic cleft
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6
Learning objective
C2.2.6—Neurotransmitter release
New
• Action potentials open voltage-gated Ca²⁺ channels in presynaptic terminals
• Ca²⁺ causes vesicle fusion and neurotransmitter exocytosis into the cleft
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7
Learning objective
C2.2.7—Excitatory postsynaptic potential
New
• Neurotransmitters diffuse and bind receptors on the postsynaptic membrane
• EPSPs depolarize the membrane and make threshold more likely
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