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AP Biology 3.5.A Mitochondria and Cellular Respiration

Practise AP Biology 3.5.A questions by connecting mitochondrial structure, electron transport, oxygen reduction and proton gradients with ATP synthesis.

Syllabus
Effective Fall 2025
Course
AP Biology

Exam points

  • locate respiration stages in the mitochondrial matrix and inner membrane
  • explain how ETC electrons establish proton gradients for oxidative phosphorylation
  • connect oxygen as terminal electron acceptor with ATP production and oxygen consumption

3.5.A—Describe the processes and structural features of mitochondria that allow organisms to use energy stored in… question 1

[Maximum number: 1]

Researchers hypothesize that the plant compound resveratrol improves mitochondrial function. To test this hypothesis, researchers dissolve resveratrol in dimethyl sulfoxide (DMSO). The solution readily passes through cell membranes. They add the resveratrol solution to mammalian muscle cells growing in a nutrient-rich solution (culture medium) that contains glucose. They measure ATP production at several time points after the addition of the resveratrol solution and find an increase in ATP production by the muscle cells.

The researchers find that resveratrol stimulates the production of components of the electron transport chain. The researchers claim that treatment with resveratrol will also increase oxygen consumption by the cells if glucose is not limiting. Justify the claim.

Write your responses to this question only on the designated pages in the separate Free Response booklet.

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