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AP Biology 2.6.A Molecule Structure and Membrane Transport

Practise AP Biology 2.6.A questions by linking ion or molecule structure to channel use, facilitated diffusion, action-potential permeability and aquaporin transport.

Syllabus
Effective Fall 2025
Course
AP Biology

Exam points

  • connect Na+ and K+ permeability changes to depolarization and repolarization
  • explain facilitated diffusion of glucose or ions through transport proteins down a gradient
  • predict reduced water movement when aquaporins are inhibited across membranes

2.6.A—Explain how the structure of a molecule affects its ability to pass through the plasma membrane question 1

[Maximum number: 2]

To investigate whether red blood cells of animals lose the ability to take in glucose from their environment as they age, scientists collected red blood cells from guinea pigs that ranged in age from one day old to seven months old. Scientists incubated an equal number of red blood cells in separate culture dishes that contained a 300 nM solution of radioactively labeled glucose. The amount of radioactively labeled glucose present inside the red blood cells of each group was measured over time.

Question (a)

(a)

Glucose transporters are required for the facilitated diffusion of glucose into red blood cells. The scientists claim that the expression of the gene encoding these transporters decreases as guinea pigs age. If the scientists' claim is supported by experimental data, predict the effect of increased age on the amount of radioactively labeled glucose present inside the cells of each group.

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Question (b)

(b)

Justify your prediction in part (c).

Write your responses to this question only on the designated pages in the separate Free Response booklet. If there are multiple parts to this question, write the part letter with your response.

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