4.6 Regulation of Cell Cycle

Describe the role of checkpoints in regulating the cell cycle.

• A number of internal controls or checkpoints regulate progression through the cell cycle.
• Interactions between cyclins and cyclindependent kinases control the cell cycle.
  • Exclusion: Knowledge of specific cyclin-CdK pairs or growth factors is beyond the scope of the AP Exam.

Describe the effects of disruptions to the cell cycle on the cell or organism.

• Disruptions to the cell cycle may result in cancer or apoptosis (programmed cell death).