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Pearson Edexcel IAL Biology 1.18 Cholesterol, HDL, LDL & CVD evidence

Practise using cholesterol, HDL and LDL evidence to explain CVD risk, atheroma formation and limits of single-factor predictions.

Syllabus
First assessment 2019
Course
Biology YBI11
Level
AS

Exam points

  • interpret graphs linking cholesterol, LDL, HDL and CVD or CHD death rates
  • explain how LDL receptors, diet or enzyme inhibition can reduce blood cholesterol
  • judge why LDL alone is an unreliable CVD predictor when HDL and other risks vary

1.18—Cholesterol, HDL, LDL and CVD evidence question 1

[Maximum number: 2]

The diagram shows a coronary heart disease (CHD) risk calculator.

Coronary Heart Disease Risk Calculator

Sex: Female
Ethnicity: Native American
Age: 50
Total Cholesterol: 196mg/dL\sqrt{196} \mathrm{mg} / \mathrm{dL}
HDL Cholesterol: 49 mg / dL
Systolic BP: 110 mmHg
Patient taking blood pressure medication: ✓\checkmark
Patient has diabetes: ✓\checkmark
Patient smokes: □

10 Year CHD Risk: 6.62\%

Explain why the risk calculator takes into account total cholesterol and HDL cholesterol levels.

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