Edexcel A-Level Biology AS 1.18 Cholesterol Hdl Ldl and Cvd Evidence Questions

Practise interpreting cholesterol, HDL and LDL evidence, explaining receptor or diet effects on blood cholesterol, and judging why LDL alone cannot predict CVD reliably.

Exam points

Interpret graphs linking cholesterol, LDL, HDL and CVD or CHD death rates.
Explain how LDL receptors, diet or enzyme inhibition can reduce blood cholesterol.
Judge why LDL alone is an unreliable CVD predictor when HDL and other risks vary.

[Maximum number: 2]

The diagram shows a coronary heart disease (CHD) risk calculator.

Coronary Heart Disease Risk Calculator

Sex: Female
Ethnicity: Native American
Age: 50
Total Cholesterol: $\sqrt{196} \mathrm{mg} / \mathrm{dL}$
HDL Cholesterol: 49 mg / dL
Systolic BP: 110 mmHg
Patient taking blood pressure medication: $\checkmark$
Patient has diabetes: $\checkmark$
Patient smokes: □

10 Year CHD Risk: 6.62\%

Explain why the risk calculator takes into account total cholesterol and HDL cholesterol levels.

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Edexcel A-Level Biology AS 1.18 Cholesterol Hdl Ldl and Cvd Evidence Questions question 1