CAIE A-Level Biology AS 5.1 Replication and Division Topic Practice

Question 1

[Maximum number: 3]

The root apical meristem is a region of undifferentiated cells in the root tips of plants. Mitosis occurs in this region.

Draw a labelled diagram to show the structure of a chromosome at late prophase of mitosis.

Question 2

[Maximum number: 1]

Which diagrams show roles of mitosis?

1

1

4

4

3

3

A

1, 2, 3 and 4

B

1, 2 and 3 only

C

1 and 2 only

D

3 and 4 only

Question 3

[Maximum number: 5]

In the immune system, a plasma cell develops from an activated B-lymphocyte. Mature plasma cells synthesise and secrete antibody molecules.

The transition from the activated B-lymphocyte to the fully mature plasma cell requires a number of mitotic cell cycles to occur. This process, which is known as clonal expansion, results in a large number of genetically identical plasma cells.

A

centrioles replicate

B

DNA polymerase catalyses the formation of phosphodiester bonds

C

condensation of chromosomes

D

nuclear envelope reassembles around each set of daughter chromosomes E centromeres move towards poles F chromosomes line up at spindle equator Table 4.1 lists the stages occurring during one cell cycle of the B-lymphocyte. These stages are not in the correct order.

Fig. 4.2

Fig. 4.2

Complete Table 4.1 by writing the letter of the event described in Fig. 4.2 that correctly matches the stage of the cell cycle listed.

Leave a blank space if there is no matching description for the stage in the list. Use each letter once only.

One of the letters in Table 4.1 has already been added for you.

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