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5. The Mitotic Cell Cycle

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  1. 5.1 Replication and Division

    1. 5.1.1Chromosome structure and telomeres

      • Chromosome structure: DNA, histone proteins, sister chromatids, centromere, telomeres

    2. 5.1.2Importance of mitosis

      • Importance of mitosis: - Growth of multicellular organisms - Replacement of damaged/dead cells - Tissue repair - Asexual reproduction

    3. 5.1.3Mitotic cell cycle

      • Mitotic cell cycle: - Interphase (G1, S phase DNA replication, G2) - Mitosis - Cytokinesis

    4. 5.1.4Telomeres

      • Role of telomeres in preventing gene loss during DNA replication

    5. 5.1.5Stem cells

      • Stem cells in cell replacement and tissue repair

    6. 5.1.6Tumour formation

      • Uncontrolled cell division and tumour formation

  2. 5.2 Chromosome Behaviour in Mitosis

    1. 5.2.1Chromosome behaviour in mitosis

      • Chromosome behaviour during mitotic cell cycle

    2. 5.2.2Cell structures in mitosis

      • Associated behaviour of nuclear envelope, cell surface membrane, spindle

    3. 5.2.3Main stages of mitosis

      • Main stages: prophase, metaphase, anaphase, telophase

    4. 5.2.4Mitosis image interpretation

      • Interpret photomicrographs, diagrams, microscope slides