5.2.A—Explain how the process of meiosis generates genetic diversity

Explain how the process of meiosis generates genetic diversity.

• Correct separation of the homologous chromosomes in meiosis I and sister chromatids in meiosis II ensures that each gamete receives a haploid (1n) set of chromosomes that comprises an assortment of both maternal and paternal chromosomes. When incorrect separation occurs (nondisjunction), gametes are no longer haploid.
• During prophase I of meiosis, non-sister chromatids exchange genetic material via a process called crossing over (recombination), which increases genetic diversity among the resultant gametes.
• Sexual reproduction in eukaryotes increases genetic variation, including crossing over, random assortment of chromosomes during meiosis, and subsequent fertilization of gametes.
  • Exclusion: Knowledge of the details of sexual reproduction cycles in various plants and animals is beyond the scope of the AP Exam.