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3.14—Mitosis and the cell cycle

Syllabus
2021
Objective
3.14
Level
AS

The cell cycle copies DNA once, then uses mitosis to make two matching cells

The cell cycle is the regulated sequence from one cell division to the next: G1 growth and normal work, S-phase DNA replication, G2 preparation and checking, M-phase nuclear division, then cytokinesis.

After S phase each chromosome has two sister chromatids. Mitosis separates those chromatids into two genetically identical nuclei, and cytokinesis partitions the cytoplasm so each daughter cell receives one nucleus.

A root-tip cell can spend much of its cycle in interphase, then pass through prophase, metaphase, anaphase and telophase before the plant cell forms a new wall between daughters.

Interphase includes G1, S and G2; it is not a single resting stage. Cytokinesis follows nuclear division and is not one of the four named stages of mitosis.

ConceptA-Level Edexcel Biology AS