Practise evaluating animal models for brain, genetics and behaviour research, including evidence quality, species limits and ethical considerations in HL questions.
Discuss the role of animal research in understanding the relationship between the brain and human behaviour.
Refer to the paper 1 section B assessment criteria when awarding marks.
The command term "discuss" requires candidates to offer a considered review of the role of animal research in understanding the relationship between the brain and human behaviour. A clear link between animal research and the understanding of human behaviour must be made.
Relevant studies include, but are not limited to:
- Meaney et al. (2000) on the role of cortisol on the hippocampus with regard to memory in mice
- Rogers and Kesner (2003) on the role of acetylcholine in formation of spatial memories in mice
- Klein (2008) on the role of exercise on neuroplasticity in rats
- Rosenzweig et al.'s (1972) study on the effect of social interaction and neuroplasticity in rats
- Weiskrantz's (1956) study of amygdala lesioning and the fear response in rhesus monkeys
- Lashley (1929) study on localization of memory in mice.
Discussion points may include, but are not limited to:
- similarities between human and animal physiology and behaviour
- generalizability of findings from animal studies to human behaviour
- ability to carry out experimental research to establish causal relationships
- use of animals in cases where it would be unethical in human studies
- ability to carry out longitudinal and generational research
- sample sizes and potential for replication.